Amethia was approved based on studies of Seasonique (Amethia is a generic version of Seasonique). In a large clinical trial, Seasonique was shown to be an effective method of birth control. In this study, 1 or 2 women out of every 100 who used Seasonique for a year became pregnant. This is quite effective, compared to many other methods of contraception. For instance, up to 14 percent of women using condoms for a year will become pregnant.

When and How to Use This Contraceptive

Some general considerations to keep in mind during treatment with Amethia include the following:
  • The medication comes in tablet form. It is taken by mouth once a day.
  • You can take Amethia with or without food. If it bothers your stomach, try taking it with food.
  • Each pack of Amethia contains 91 pills. Once you finish a pack, start a new pack the next day, without letting any days pass in between packs. You will probably get your period during the last seven days of the pack.
  • It is normal to experience breakthrough bleeding or spotting between periods while taking Amethia. Continue taking the pills as normal.
  • It is important that you take Amethia every day and at the same time each day. Try to pick a time that will be easy to remember, such as at bedtime or breakfast. If you have trouble remembering, please talk with your healthcare provider, as missing pills increases your risk of pregnancy.
  • Make sure you know exactly what to do if you miss any pills. In some circumstances, you may need to use a backup method of contraception, such as condoms, for seven days.
  • For the contraceptive to work properly, it must be taken as prescribed. Amethia will not work if you stop taking it.
Last reviewed by: Kristi Monson, PharmD
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