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Drug Interactions With Apri

Apri Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Apri is combined with any of the drugs listed above.
Aminoglutethimide (Cytadren)
Taking Apri with aminoglutethimide may increase your risk of unintentional pregnancy. Talk with your healthcare provider before using these medications together. You may need to use a backup method of contraception (such as condoms).
Antibiotics
There have been reports of accidental pregnancy occurring in women taking birth control pills together with certain antibiotics. However, the significance of this interaction is still uncertain. Some antibiotics are more likely to cause problems than others. If you are taking an antibiotic, ask your healthcare provider if you need to use a backup method of contraception.
Aprepitant (Emend)
Aprepitant can make Apri less effective, perhaps increasing your chance of pregnancy. Talk with your healthcare provider before using these medications together. You may need to use a backup method of contraception.
Atorvastatin (Lipitor)
Atorvastatin may increase the level of Apri in your blood, which may increase your risk of Apri side effects. Check with your healthcare provider before taking these medications together.
Barbiturates
Barbiturates may cause your body to metabolize the hormones in Apri too quickly, increasing your risk of pregnancy. Ask your healthcare provider if you should use a different method of contraception while taking a barbiturate.
Cyclosporine (Gengraf, Neoral, Sandimmune)
Apri may increase the level of cyclosporine in your blood, increasing the chance of side effects of cyclosporine. Talk with your healthcare provider before taking these medications together. You may need a lower dose of cyclosporine, or you may need to switch to a different method of contraception.
Last reviewed by: Kristi Monson, PharmD
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