Drug Interactions With Benzphetamine

Benzphetamine Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when benzphetamine is combined with any of the drugs listed above.
Any Other Weight Loss Medications
Do not combine benzphetamine with any other weight loss medications or supplements, as doing so may increase the risk of pulmonary hypertension, a rare but often fatal disorder.
Because you may eat less while taking benzphetamine, your healthcare provider may need to decrease your insulin dose.
Monoamine Oxidase Inhibitors (MAOIs)
Taking benzphetamine and MOA inhibitors together can cause life-threatening side effects, such as very high blood pressure. Do not take benzphetamine if you have taken an MAOI within the past 14 days.
Sodium Bicarbonate
Sodium bicarbonate (when taken as a medication, not in normal food use) can increase the level of benzphetamine in your blood, increasing your risk of benzphetamine side effects. Check with your healthcare provider before taking these medications together.
Tricyclic Antidepressants
Taking benzphetamine with a tricyclic antidepressant can increase the risk of dangerous side effects from either medication. Check with your healthcare provider before combining benzphetamine with a tricyclic antidepressant.
Tromethamine (THAM)
Tromethamine can increase the level of benzphetamine in your blood, increasing the risk of side effects. Talk with your healthcare provider before taking tromethamine and benzphetamine together.

Final Thoughts on Drug Interactions With Benzphetamine

It is possible that not every drug interaction with benzphetamine was discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about the benzphetamine drug interactions that may apply to you.

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Last reviewed by: Kristi Monson, PharmD
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