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Birth Control Pill Drug Interactions

Modafinil (Provigil)
Modafinil may make birth control pills less effective, possibly increasing your risk of pregnancy. Talk with your healthcare provider, as you may need to use a backup method of contraception.
Protease Inhibitors
Using birth control pills with a protease inhibitor may increase your risk of pregnancy and may make the protease inhibitor less effective. Talk with your healthcare provider before using birth control pills with a protease inhibitor.
St. John's Wort
St. John's wort, a commonly used herbal supplement, may decrease the effectiveness of birth control pills, potentially increasing the chance of pregnancy. In general, you should not take St. John's wort while using birth control pills.

Final Thoughts on Birth Control Pill Drug Interactions

It is possible that not every drug interaction was discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about the birth control pill drug interactions that may apply to you. Since many women get birth control pills from a source other than their pharmacies, such as a women's health clinic, make sure your pharmacist knows that you take birth control pills. Your pharmacist will not check for drug interactions if he or she does not know that you are taking birth control pills.
Last reviewed by: Kristi Monson, PharmD
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