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Botox Injections for Wrinkles

Botox® (onabotulinumtoxinA, previously known as botulinum toxin type A) is a prescription medication approved for several different uses. Using the injections for wrinkles is one of the most common uses of Botox.
Botox is approved to temporarily reduce the appearance of "frown lines" between the eyebrows and crow's feet. The beneficial effects of Botox for wrinkles and frown lines between the eyebrows last about three to four months. In order to maintain the effects, you will need to receive Botox injections periodically.
Studies have evaluated Botox for eyebrow frown lines. In studies, up to 82 percent of people who received injections saw significant improvement one week afterwards, compared to just 9 percent who had received placebo injections (which did not contain any active ingredient). This effect lasted for at least 60 days, after which time the effects appear to gradually decrease. At 120 days after the injections, 39 percent of people who received Botox still saw improvement.
(Click Botox Uses for more information on how this product works to reduce wrinkles, to learn about other approved uses of this medication, and find out how this drug works for these other uses.)
Last reviewed by: Kristi Monson, PharmD
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