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How Long Does Botox Last?

Botox® (onabotulinumtoxinA, previously known as botulinum toxin type A) is a prescription drug commonly used to improve the appearance of facial lines. It can also be used to treat various conditions, including severe sweating and muscle spasm of the head and neck.
Many people wonder, "How long does it last?" In studies where Botox was used to treat frown lines between the eyebrows, the results lasted for at least 60 days, after which time the effects appeared to gradually decrease. At 120 days after the injections, 39 percent of people who received Botox still saw improvement.
For cervical dystonia (muscle spasms of the head and neck), studies showed that Botox injections help relieve neck pain and abnormal head positioning, compared to placebo injections (which contain no active ingredient). In most people, the beneficial effects were gone after about three months.
Studies of Botox for severe underarm sweating showed that up to 86 percent of people who received injections decreased their sweat production by 50 percent or more. The beneficial effects lasted an average of 200 days.
For neurological bladder problems, studies have shown that repeat treatment was needed around 42 weeks to 48 weeks for most people. For overactive bladder, repeat treatment was needed about every 24 weeks, on average.
(Click Botox for more information on how long the drug lasts, to find out how it works, and to learn about the warnings associated with this medication.)
Last reviewed by: Kristi Monson, PharmD
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