Conjugated Estrogens

How Do They Work?

Conjugated estrogens is a mixture of equine (horse) estrogens. Even if they are made synthetically from plant sources, they are still "horse" hormones, not human hormones. However, this alone should not be a cause for concern, as many pharmaceuticals (such as insulin or heparin) are or were originally derived from various animal sources.
Conjugated estrogens help to relieve menopausal symptoms by replacing the estrogen that the ovaries no longer produce. Because estrogen helps to keep the bones strong, the decrease in estrogen during menopause causes a significant weakening of the bones, often resulting in osteoporosis. By providing estrogen, conjugated estrogens can help prevent these menopause-related bone changes.

Conjugated Estrogens Dosing Information

The dosage your healthcare provider recommends will vary, depending on a number of factors, including:
  • The particular conjugated estrogens product
  • The medical condition being treated
  • How you respond to conjugated estrogens
  • Whether you have had a hysterectomy (if you have not, you will need to take a progestin medication as well)
  • Other medical conditions you may have.
As always, do not adjust your dose unless your healthcare provider specifically instructs you to do so.
(Click the following links for more information about the uses of the various conjugated estrogens products:
Last reviewed by: Kristi Monson, PharmD
Calcium and Strong Bones