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Cyclessa Drug Interactions

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The following sections explain in detail the potentially negative interactions that can occur when Cyclessa is combined with any of the drugs listed above.
Aminoglutethimide (Cytadren)
Taking Cyclessa and aminoglutethimide together increases the risk of pregnancy. Do not combine these medications without checking with your healthcare provider first. You may need to use a backup method of contraception, such as condoms.
Antibiotics
There have been reports of accidental pregnancy occurring in women taking birth control pills with certain antibiotics. However, it is still uncertain how significant this interaction may be. Some antibiotics are more likely to cause problems than others. Ask your healthcare provider if you need a backup method of contraception any time you take an antibiotic.
Aprepitant (Emend)
Aprepitant may make Cyclessa less effective, perhaps increasing your chance of pregnancy. Talk with your healthcare provider before using these medications together. You may need to use a backup method of contraception. Aprepitant is commonly used by people undergoing chemotherapy, and it is usually important for women having chemotherapy to avoid pregnancy.
Atorvastatin (Lipitor)
Atorvastatin may increase the level of Cyclessa in your blood, which may increase your risk of Cyclessa side effects. Check with your healthcare provider before taking these medications together.
Barbiturate Medications
Barbiturates may cause your body to metabolize the hormones in Cyclessa too quickly, possibly increasing your risk of pregnancy. Ask your healthcare provider if you should use a different method of contraception while taking a barbiturate.
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD



