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Depo-SubQ Provera 104 and Breastfeeding

It is typically considered safe for women to use depo-subQ Provera 104 (medroxyprogesterone subcutaneous injection) while breastfeeding. Although this drug does pass through breast milk, it does not appear to harm a nursing baby. In fact, if a woman wants to use a hormonal form of birth control while breastfeeding, a progestin-only contraceptive like depo-subQ Provera 104 is generally recommended instead of products that contain estrogen.

Can Breastfeeding Women Use Depo-SubQ Provera 104?

depo-subQ Provera 104® (medroxyprogesterone subcutaneous injection) is an injectable form of birth control that is given once every three months. It is also approved to help manage the pain from endometriosis, a condition in which the cells that normally line the inside the uterus grow outside of the uterus.
depo-subQ Provera 104 passes through breast milk. However, it is generally considered safe for use while breastfeeding.

More Information on Depo-SubQ Provera 104 and Breastfeeding

Although depo-subQ Provera 104 is known to pass through breast milk, it does not appear to harm a nursing baby. It also does not affect breast milk production.
Birth control that contains estrogen is generally not recommended for women who are nursing. If hormonal birth control is going to be used while nursing, progestin-only birth control (such as depo-subQ Provera 104) is preferred. This is because estrogen can increase a woman's risk for a serious blood clot in the four weeks after childbirth and can decrease breast milk supply.
It is generally recommended that women wait to receive their first depo-subQ Provera 104 shot until six weeks after giving birth. This helps reduce the amount of the medicine passed to the baby in the early weeks of life.
(Click Breastfeeding and Birth Control to learn more about your options for birth control while breastfeeding.)

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Last reviewed by: Kristi Monson, PharmD
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