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Depo-SubQ Provera 104 Drug Interactions

Depo-SubQ Provera 104 Drug Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when depo-subQ Provera 104 is combined with any of the drugs listed above.
Antibiotics
There have been reports of women becoming pregnant while taking antibiotics with hormonal contraceptives, including depo-subQ Provera 104. These reports suggest that antibiotics could make the contraceptives less effective. At this time, it is not entirely clear whether there is actually an interaction between these medicines, however. If you are using depo-subQ Provera 104 as a form of birth control, you may want to use a backup birth control method while taking an antibiotic, just to be safe.
Anti-Seizure Medications
depo-subQ Provera 104 can cause a loss of bone density, especially with prolonged use. Certain anti-seizure medications (also called anti-epileptics) can also affect bone health. Taking these medications together may further increase your risk for bone loss, osteoporosis, and fractures. Talk to your healthcare provider about this potential interaction before taking an anti-seizure medicine with depo-subQ Provera 104.
Corticosteroids
depo-subQ Provera 104 can cause a loss of bone density, especially with prolonged use. Corticosteroid medications can also affect bone health. Combining depo-subQ Provera 104 with a corticosteroid may further increase your risk for bone loss, osteoporosis, and fractures. Talk to your healthcare provider about this potential interaction before taking these medications together.
Cyclosporine
depo-subQ Provera 104 may increase the level of cyclosporine in your blood, potentially increasing the chance of side effects. Your healthcare provider may choose to monitor you more closely, and may give you a lower cyclosporine dose, if you take these medications together.

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↶ An Overview of Interactions With Depo-SubQ Provera 104
‣ Final Thoughts
Last reviewed by: Kristi Monson, PharmD
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