Side Effects of Diethylpropion

Dry mouth or unpleasant taste, blurred vision, drowsiness, and headache are some of the possible side effects of diethylpropion. Certain side effects, while occurring infrequently, are potentially serious and should be reported to a healthcare provider immediately, such as strange behavior, hallucinations, or high blood pressure. In most cases, however, diethylpropion side effects only occur when too much of the drug is taken.

An Introduction to Side Effects of Diethylpropion

As with any medicine, side effects are possible with diethylpropion hydrochloride (Tenuate®); however, not everyone who takes the drug will experience side effects. In fact, most people tolerate it quite well. In most cases, side effects occur when too much diethylpropion is taken.
(This article covers many, but not all, of the possible side effects with diethylpropion. Your healthcare provider can discuss a more complete list of diethylpropion side effects with you.)

Side Effects of Diethylpropion to Report

Some side effects with diethylpropion, while occurring infrequently, are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
  • Signs of a life-threatening side effect known as primary pulmonary hypertension, such as:
    • Difficulty breathing
    • Chest pain
    • Fatigue or weakness
    • Dizziness or fainting
    • Swelling of the ankles
    • Blue lips or skin
  • A stroke
  • High blood pressure (hypertension)
  • A rapid heart rate (tachycardia)
  • Feelings of a rapidly or forcefully beating heart (known as heart palpitations)
  • Seizures
  • Frequent infections or unusual bruising or bleeding (which may be a sign of low blood counts)
  • More outgoing or aggressive behavior than normal
  • Strange behavior
  • Enlarged breasts (in men)
  • Hallucinations (seeing, hearing, or feeling things that are not really there)
  • Agitation or restlessness
  • Depression
  • A desire or need to take diethylpropion more frequently or at a higher dose than prescribed
  • Signs of an allergic reaction, such as:
    • Unexplained rash
    • Hives
    • Itching
    • Unexplained swelling
    • Wheezing
    • Difficulty breathing or swallowing.
Last reviewed by: Kristi Monson, PharmD
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