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Diflucan for Yeast Infections

Diflucan® (fluconazole) is an antifungal medication that is available by prescription only. Although this drug is approved to treat many different types of fungal infections, many healthcare providers will prescribe it for yeast infections.
Unlike most other yeast infection medications, Diflucan is not used vaginally; it works through the bloodstream to treat yeast infections. The drug can either be taken by mouth (in tablet or oral solution form) or administered by injection.
Diflucan belongs to a group of medications known commonly as "azole" antifungals. It works by inhibiting an enzyme that is used by fungal cells to make ergosterol, an important component of the fungal cell membrane. As a result, there is not enough ergosterol and too much of the compounds that are normally used to make ergosterol, and fungal growth is inhibited.
(Click Diflucan Uses for more information about using this medicine for yeast infections, what else it is used for, and possible off-label uses.)
Last reviewed by: Kristi Monson, PharmD
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