Over-the-Counter Diflucan

There is currently no over-the-counter Diflucan® (fluconazole). It is an antifungal medication that is available by prescription only. The medication is approved to treat different types of fungal infections (such as yeast infections and thrush) and can also be used to prevent fungal infections in people undergoing bone marrow transplantations.
Unlike most other yeast infection medications, Diflucan is not used vaginally. It works through the bloodstream to treat fungal infections. The medicine comes in tablet, suspension (oral liquid), and injectable form, and is available in the following strengths:
(Click Diflucan for more information about how this prescription drug works, when and how to take Diflucan, and potential side effects of this medication.)
Last reviewed by: Kristi Monson, PharmD
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