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Enpresse Side Effects

Common Side Effects of Enpresse

All prescription medications must be shown to be safe and effective in clinical studies before they are approved in the United States. For most medications, clinical studies involve two different groups; one group of people is given the actual medication, while another group is given a placebo (a "sugar pill" with no active ingredients). Usually, the subjects do not know if they are taking the real medication or the placebo.
During the clinical studies, the side effects in both groups are carefully documented. This way, it is possible to see what side effects occur, how often they appear, and whether they are actual side effects of the medication. However, it is not usually possible to use a placebo in clinical trials for contraceptives, as this would lead to many unintentional pregnancies.
Since it is difficult to obtain much information about side effects from studies that do not use a placebo (since there is no way of knowing whether any particular problem is actually a side effect of the medication), only vague information is available about Enpresse side effects. In fact, the side effects listed in the prescribing information of Enpresse are actually side effects of all birth control pills in general (not necessarily of Enpresse in particular). Some of the common bothersome (but usually not dangerous) side effects of birth control pills include:
  • Breakthrough bleeding and spotting between periods (especially for the first few cycles)
  • Nausea and vomiting
  • Changes in your eyes that make it more difficult to wear contact lenses
  • Acne (although many women find that birth control pills actually improve acne)
  • Bloating
  • Breast tenderness or other breast changes (such as swelling)
  • Headaches (although birth control pills can improve headaches in some women)
  • Changes in sex drive (often a decrease, rather than an increase).
Last reviewed by: Kristi Monson, PharmD
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