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Precautions and Warnings With Enpresse

Specific Warnings and Precautions for Enpresse

Warnings and precautions to be aware of prior to using Enpresse include the following:
  • Like any birth control pill, Enpresse does not protect against sexually transmitted diseases (STDs), including HIV or AIDS. As a result, it is often wise to use condoms in addition to Enpresse, in order to prevent the transmission of STDs.
  • Combined oral contraceptives (including Enpresse) can cause life-threatening conditions such as heart attacks, strokes, and blood clots. The risk is quite small for healthy, young, nonsmoking women. Make sure to tell your healthcare provider if you have ever had a blood clot, stroke, heart attack, or chest pain. Smoking cigarettes greatly increases the risk of these serious Enpresse side effects. This risk is particularly high for smokers over the age of 35.
  • Enpresse is very effective for preventing pregnancy when taken correctly. However, it becomes much less effective if taken incorrectly. Most cases of accidental pregnancy while taking "the pill" (including Enpresse) are due to incorrect usage. Make sure you understand exactly how to take Enpresse (including how and when to start it and what to do if you miss pills).
  • Combined oral contraceptives may slightly increase the risk of breast cancer or cervical cancer, although this is an unresolved issue. However, combined oral contraceptives seem to help protect women against ovarian and uterine cancer.
  • Enpresse can interact with a number of different medications (see Drug Interactions With Enpresse for more information).
  • Oral contraceptives increase the risk of benign (non-cancerous) liver tumors. Very rarely, these tumors can rupture and cause serious problems.
  • Hormonal contraceptives (such as Enpresse) may make gallbladder disease worse. If you have had a problem with your gallbladder, Enpresse may not be the best contraceptive method for you.
  • Enpresse may increase blood sugar, particularly in women with diabetes. Your healthcare provider may need to monitor you more closely. Let your healthcare provider know if you have any sudden vision changes, as this may be a sign of a blood clot in the eyes (a possible side effect of Enpresse and other hormonal contraceptives).
  • Hormonal contraceptives (including Enpresse) can increase your blood pressure. This can be a problem if you already have high blood pressure.
  • Enpresse can change your menstrual bleeding patterns. Some women have breakthrough bleeding (bleeding between periods), while others may not have a period at all. It is normal to have shorter and lighter periods while using Enpresse. If you notice any unusual changes in your bleeding patterns, let your healthcare provider know. If you miss a period, you should make sure you are not pregnant.
  • Enpresse can affect your cholesterol. Your healthcare provider may need to check your cholesterol levels after you start Enpresse, especially if you already have high cholesterol.
  • Sometimes, hormonal contraceptives may make depression worse. Let your healthcare provider know if you develop new or worsening depression symptoms.
  • Occasionally, Enpresse (as well as any other hormonal contraceptive) can cause eye changes that make it more difficult to wear contact lenses.
  • Enpresse is considered a pregnancy Category X medication. This means that it should not be used during pregnancy (see Triphasil and Pregnancy).
  • Contraceptive hormones (such as the ones in Enpresse) pass through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to taking the drug (see Triphasil and Breastfeeding). Combined hormonal contraceptives (such as Enpresse) are usually not recommended for breastfeeding women.
Last reviewed by: Kristi Monson, PharmD
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