Precautions and Warnings With Estradiol Vaginal Cream

Make sure to talk to your healthcare provider about the precautions and warnings with estradiol vaginal cream to help ensure safe treatment. Certain women should not use the medication, including those who are pregnant, have liver disease, or have a history of breast cancer. It is also important to know that estradiol vaginal cream can increase the risk of dementia, breast cancer, and gallbladder disease.

Estradiol Vaginal Cream: What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to using estradiol vaginal cream (Estrace® Vaginal Cream) if you have:
Also, let your healthcare provider know if you:
  • Are pregnant or thinking of becoming pregnant
  • Are breastfeeding
  • Have an upcoming surgery
  • Smoke cigarettes.
Make sure to tell your healthcare provider about any other medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
Last reviewed by: Kristi Monson, PharmD
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