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Estradiol Vaginal Tablets

When and How to Use Estradiol Vaginal Tablets

General considerations for when and how to use estradiol vaginal tablets include the following:
  • Each tablet comes packaged in a single-use, disposable applicator tube. The applicator is inserted vaginally (much like a tampon), and the tablet is released by pushing the plunger.
  • Your package of estradiol vaginal tablets comes with detailed instructions on how to use the tablets.
  • Dispose of the applicator just as you would a plastic tampon applicator (do not flush it).
  • Estradiol vaginal tablets are typically used daily for the first two weeks; after that, it is usually used just twice a week.
  • If you accidentally release the tablet from the applicator before inserting it vaginally, do not try to replace the tablet into the applicator. Simply throw it away and use a new one.
  • For the medication to work properly, it must be taken as prescribed.

Who Makes Estradiol Vaginal Tablets?

Estradiol vaginal tablets are made by Novo Nordisk.

Strengths of Estradiol Vaginal Tablets

Estradiol vaginal tablets come in the one strength -- estradiol vaginal tablets 10 mcg (previously a higher strength of 25 mcg was available, but that product was discontinued).
Each tablet comes in a disposable applicator, and each package contains 8 or 18 tablets (and applicators).

Generic Estradiol Vaginal Tablets

At this time, there are no generic versions of estradiol vaginal tablets licensed for sale (see Generic Vagifem for more information).
Last reviewed by: Kristi Monson, PharmD
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