Estradiol Valerate Dosage

When determining your estradiol valerate dosage, your healthcare provider will consider several factors, such as the medical condition being treated and other medical conditions you have. For treating menopausal symptoms and hormone deficiencies, the typical estradiol valerate dose is 10 mg to 20 mg injected once a month. When treating prostate cancer symptoms, the estradiol valerate dose is much higher, at least 30 mg injected once every one or two weeks.

Estradiol Valerate Dosage: An Introduction

The dose of estradiol valerate (Delestrogen®) your healthcare provider recommends will vary, depending on a number of factors, including:
  • How you respond to estradiol valerate
  • The medical condition being treated
  • Other medical conditions you may have.
As always, do not adjust your estradiol valerate dose unless your healthcare provider specifically instructs you to do so.

Estradiol Valerate Dosing for Menopause Symptoms

It is typically recommended that hormone replacement therapy (including estradiol valerate) should be taken at the lowest effective dose for the shortest possible period of time for treating menopause symptoms. However, the most effective dose (and how long it should be taken) can vary considerably from one woman to the next.
The recommended estradiol valerate dose is 10 mg to 20 mg injected once every a month. If you still have a uterus (if you have not had a hysterectomy), it is recommended that you take a progestin medication along with estradiol valerate, in order to help prevent cancer of the lining of the uterus.

Estradiol Valerate Dosing for Prostate Cancer

For prostate cancer, the recommended estradiol valerate dosage is 30 mg (or more) injected once every one or two weeks. This is a very high estradiol valerate dosage (much higher than recommended for other uses).
Last reviewed by: Kristi Monson, PharmD
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