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Side Effects of Estradiol Valerate

Common Estradiol Valerate Side Effects

Common side effects of estrogens, such as estradiol valerate, include (but are not limited to):
  • Vaginal yeast infections
  • Nausea and vomiting
  • Headaches
  • Breast tenderness
  • Irregular vaginal bleeding or spotting
  • Abdominal (stomach) cramps or bloating
  • Hair loss
  • High blood sugar (hyperglycemia)
  • High blood pressure (hypertension)
  • Fluid retention
  • Enlargement of benign tumors of the uterus (uterine fibroids).

Final Thoughts on Estradiol Valerate Side Effects

It is possible that you may experience some or none of the estradiol valerate side effects listed in this article. Unfortunately, it can be difficult to tell whether any particular side effect (such as nausea) is caused by estradiol valerate or by other factors. Therefore, make sure to let your healthcare provider know if you develop any side effects while taking estradiol valerate, or if something "just does not seem right." While it may not be a side effect of the medication, your healthcare provider will be able to diagnose and treat the problem.
Last reviewed by: Kristi Monson, PharmD
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