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What Is Estradiol Valerate Used For?

Estradiol Valerate Use in Younger Women

Sometimes, younger women do not produce enough estrogen, for a variety of reasons. In some cases, the ovaries simply stop working too soon, for unknown reasons. In other instances, certain medications (such as chemotherapy) have affected the ability of the ovaries to function properly. Some women have had their ovaries surgically removed. Or, perhaps, the ovaries never started working properly in the first place (which results in delayed or absent puberty). In all of these situations, estradiol valerate can be used as a substitute for the estrogen that the ovaries cannot produce.

Estradiol Valerate Use for Cancer

High doses of estradiol valerate can work to relieve the symptoms of advanced prostate cancer. It works by suppressing testosterone and other male hormones that "feed" prostate cancer. Estradiol valerate will not cure prostate cancer and should only be used to relieve symptoms of the cancer. This is known as "palliative" cancer therapy.

Estradiol Valerate Use in Children and Teens

Estradiol valerate is specifically approved for use in children or teens, although it is sometimes used in teens with delayed or absent puberty. Discuss the risks and benefits of using estradiol valerate with your child's healthcare provider.

Off-Label Estradiol Valerate Uses

On occasion, your healthcare provider may recommend estradiol valerate for something other than the conditions listed above. This is called an "off-label" use. At one point, hormone replacement therapy was used off-label for preventing heart disease and dementia (such as Alzheimer's disease), but these are no longer considered legitimate off-label uses. Sometimes hormones are used to promote youthfulness. Again, this is not generally accepted as a legitimate off-label estradiol valerate use.
Estradiol valerate is sometimes used off-label by men who are undergoing a sex reassignment process ("sex change").

More Headlines in What Is Estradiol Valerate Used For?

↶ What Is Estradiol Valerate Used For?
↶ Estradiol Valerate Use for Menopause
Last reviewed by: Kristi Monson, PharmD
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