Advertisement

Drug Interactions With Estropipate

More Information on Interactions With Estropipate

The following sections explain in detail the potentially negative interactions that can occur when estropipate is combined with any of the substances listed above.
Barbiturate Medications
Barbiturates may cause your body to metabolize the hormones in estropipate too rapidly, possibly leading to low levels of estropipate in the body. This can make estropipate less effective, but it is not a serious drug interaction.
Certain Antifungals or Antibiotics
Some antibiotic or antifungal medications may decrease the ability of your liver to metabolize estropipate, potentially leading to high levels of estropipate in the body. This may increase the risk of side effects of estropipate. Check with your healthcare provider before combining estropipate with certain antibiotics or antifungals.
Certain Seizure Medications
Some seizure medications may cause your body to metabolize the hormones in estropipate too quickly, possibly leading to low levels of estropipate in the body. Although this can make estropipate less effective, it is not a dangerous drug interaction.
Cyclosporine (Gengraf, Neoral, Sandimmune)
Estropipate may increase the level of cyclosporine in your blood, possibly increasing the chance of side effects of cyclosporine. Talk with your healthcare provider before taking these medications together. You may need a lower cyclosporine dose, or you may need to switch to one of the many estropipate alternatives.
Grapefruit Juice
Grapefruit juice may decrease the ability of your liver to metabolize estropipate, possibly leading to high levels of estropipate in the body. This may increase the risk of side effects.
Last reviewed by: Kristi Monson, PharmD
Advertisement
Feed Your Adult ADHD Brain