Drug Interactions With Estropipate

Several medications can cause drug interactions with estropipate, including protease inhibitor HIV medicines, certain antifungals or antibiotics, rifamycin antibiotics, and some seizure medications. These interactions can potentially increase your risk of developing side effects or decrease the effectiveness of estropipate. If estropipate drug interactions are a concern, your healthcare provider may monitor you more closely and adjust your dosages.

An Introduction to Estropipate Drug Interactions

Estropipate (Ogen®) can potentially interact with various other medications and substances. Some of the products that may lead to estropipate drug interactions include:
  • Barbiturates, such as:
    • Amobarbital (Amytal®)
    • Butalbital (Fioricet®, Fiorinal®)
    • Pentobarbital (Nembutal®)
    • Phenobarbital (Luminal®)
    • Secobarbital (Seconal®)
  • Certain antifungal medications or antibiotics, such as:
    • Clarithromycin (Biaxin®)
    • Erythromycin (Ery-Tab®)
    • Isoniazid (Nydrazid®)
    • Itraconazole (Sporanox®)
    • Ketoconazole (Nizoral®)
    • Miconazole
    • Telithromycin (Ketek®)
  • Certain seizure medications, such as:
  • Rifamycin antibiotics, including rifabutin (Mycobutin®), rifampin (Rifadin®), and rifapentine (Priftin®)
  • St. John's wort (Hypericum perforatum), an herbal supplement
  • Thyroid replacement medications, such as:
Last reviewed by: Kristi Monson, PharmD
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