Before starting a new drug, make sure you are aware of its precautions and warnings. With estropipate, it is important to be aware of potential drug interactions and to let your healthcare provider know if you have heart disease, asthma, or diabetes before starting treatment. You should not take estropipate if you have undiagnosed abnormal genital bleeding, liver disease, or a history of breast cancer.
Kidney disease, including kidney failure (renal failure)
An underactive thyroid (hypothyroidism)
Endometriosis
Unexplained vaginal bleeding
Any allergies, including allergies to drugs, foods, preservatives, or dyes.
Also, let your healthcare provider know if you:
Have an upcoming surgery
Smoke cigarettes
Are pregnant or thinking of becoming pregnant
Are breastfeeding.
Make sure to tell your healthcare provider about any other medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.