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What Is Estropipate Used For?

Estropipate is used for replacing the estrogen that the ovaries no longer produce. It is a hormone replacement medication that is approved for treating menopausal symptoms, preventing osteoporosis in postmenopausal women, and treating hormone deficiency in younger women whose ovaries do not produce enough estrogen. Healthcare providers have recommended off-label estropipate uses in the past, but the drug is no longer used for such purposes.

What Is Estropipate Used For? -- An Overview

Estropipate (Ogen®) is a prescription medication that contains an estrogen hormone. It is approved for the following uses:
  • Treatment of menopausal symptoms, such as hot flashes and vaginal dryness
  • Prevention of osteoporosis in postmenopausal women
  • Treatment of hormone deficiency in younger women whose ovaries do not produce enough estrogen.
Estropipate Uses for Menopause
Menopause is a normal change in a woman's life when she stops having her period. Technically, a woman has reached menopause when she has not had a period for 12 months in a row and there are no other causes for this change. Menopause symptoms include:
  • Hot flashes (hot flushes)
  • Night sweats and sleeping problems, including insomnia
  • Vaginal changes, such as dryness or irritation
  • Changes in your period, including abnormal bleeding or "spotting"
  • Thinning and weakening of your bones
  • Mood changes
  • Urinary problems
  • Problems with concentration or memory
  • Less interest in sex and changes in sexual response
  • Weight gain or increase in body fat around your waist
  • Hair thinning or hair loss.
For some women, these symptoms are quite severe and some form of menopause relief may be necessary. This may include medications, natural menopause relief remedies, or non-medical ways to deal with the symptoms.
For menopause treatment, estropipate should be used at the lowest effective dose for the shortest period necessary.
Because estropipate (or any other estrogen treatment) without progesterone can increase the risk of precancerous or cancerous changes in the uterus, it must be combined with a progestin (either continuously or intermittently) in women who still have a uterus. If you have had a hysterectomy, you can take estropipate alone, without any progesterone.

More Headlines in What Is Estropipate Used For?

‣ Estropipate Use in Children and Teens
‣ Off-Label Estropipate Uses
Last reviewed by: Kristi Monson, PharmD
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Men and Osteoporosis