Fertility Drugs

Fertility Drugs and Ovarian Cancer

Concern over a link between fertility drugs and ovarian cancer came from studies published in the early 1990s that suggested the risk of ovarian cancer might be significantly increased in women exposed to fertility drugs. However, more recent studies have failed to corroborate a strong association between fertility drugs and ovarian cancer in the general population.
One study evaluated more than 12,000 women and did not find a strong link between ovulation-stimulating fertility drugs (clomiphene and gonadotropins) and ovarian cancer. The researchers also concluded that slight but non-significant elevations in risk with fertility drugs among certain subgroups support the need to continue monitoring long-term risks. The study was published in the June 2004 issue of Obstetrics and Gynecology, the journal of the American College of Obstetricians and Gynecologists.
Last reviewed by: Arthur Schoenstadt, MD
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