Drug Interactions With Junel

Some of the medications that can interfere with Junel include barbiturates, modafinil, and protease inhibitors. Drug interactions with Junel can lead to an increased risk of pregnancy and side effects, among other things. Therefore, before taking this birth control pill, it's important to talk with your healthcare provider about the Junel drug interactions that may apply to you.

Drug Interactions With Junel: An Overview

Junel™ (norethindrone/ethinyl estradiol) can potentially interact with several other medicines. Many of these interactions can be severe enough to cause accidental pregnancy, and a backup method of birth control may be recommended.
(Junel is equivalent to Loestrin® and Microgestin® birth control pills. The information in this article also applies to both of these medications.)
Many medications can interact with Junel, so it is a good idea to make sure that all your healthcare providers know you are taking the drug. Any time you start a new medication, check with your healthcare provider about possible interactions with Junel. Some of the medicines that may lead to Junel drug interactions include:
  • Aminoglutethimide (Cytadren®)
  • Antibiotics
  • Aprepitant (Emend®)
  • Barbiturate medications, such as:
    • Amobarbital (Amytal®)
    • Butalbital (Fioricet®, Fiorinal®)
    • Pentobarbital (Nembutal®)
    • Phenobarbital (Luminal®)
    • Primidone (Mysoline®)
    • Secobarbital (Seconal®)
Last reviewed by: Kristi Monson, PharmD
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