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Side Effects of Leena

There are possible side effects of any birth control pill (including Leena). Some common side effects of Leena include headaches, nausea, and breast tenderness. In most cases, the side effects are minor and can easily be treated. However, there are more serious side effects that can occur with Leena, such as chest pain, vision changes, migraines, and depression.

An Introduction to Side Effects of Leena

As with any medicine, Leena® (norethindrone/ethinyl estradiol) can cause side effects. However, not every woman who uses the contraceptive will experience side effects. In fact, most women tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are easily treated by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with Leena. Your healthcare provider can discuss a more complete list of Leena side effects with you. Leena is a generic version of Tri-Norinyl® and is also equivalent to Aranellebirth control pills. The information in this article applies to both of these medications as well.)

Side Effects of Leena to Report

Because it is difficult to obtain much information about possible side effects from studies that do not use a placebo, only vague information is available about Leena side effects. In fact, the side effects listed in the prescribing information of Leena are actually the possible side effects of all birth control pills in general (not necessarily of Leena in particular).
There are a number of side effects with Leena that you should report to your healthcare provider. These include, but are not limited to:
  • Depression or other emotional changes
  • Migraines (or changes in your migraines, if you have had them before)
  • Breast lumps
  • High blood pressure (hypertension)
  • High cholesterol
  • Signs of a stroke, such as vision or speech changes, weakness or numbness in an arm or leg, and a severe headache
  • Signs of liver damage, such as yellowing of the whites of the eyes or skin (jaundice), dark urine, and upper right abdominal pain (stomach pain)
  • Signs of a blood clot in the leg, such as pain in the calf, leg cramps, and leg or foot swelling
  • Signs of a blood clot in the lung, such as shortness of breath, sharp chest pain, or coughing up blood
  • Chest pain or heaviness, which may be signs of a heart attack
  • Sudden loss of vision or vision changes, which can be a sign of a blood clot in the eye
  • Heavy vaginal bleeding between periods (light bleeding or spotting is normal)
  • Signs of an allergic reaction, including an unexplained rash, hives, itching, unexplained swelling, wheezing, or difficulty breathing or swallowing.
Last reviewed by: Kristi Monson, PharmD
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