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Drug Interactions With Leuprolide Acetate Depot

Diabetes medications, such as metformin, insulin, sulfonylureas, and alpha-glucosidase inhibitors, are the only products expected to cause drug interactions with leuprolide acetate depot. If you have diabetes, your healthcare provider may adjust the doses of your diabetes medications and have you check your blood sugar more often during treatment with leuprolide acetate depot.

An Overview of Leuprolide Acetate Depot Interactions

Leuprolide acetate depot (Lupron Depot®) is a prescription hormone medication that is given as an injection. Leuprolide acetate depot is not expected to interact with most medications. However, it may react with drugs used to treat diabetes, including:
  • Alpha-glucosidase inhibitors, such as:

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Last reviewed by: Kristi Monson, PharmD
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