Precautions and Warnings With Levonorgestrel-Releasing Intrauterine System

Who Should Not Use Levonorgestrel-Releasing Intrauterine System?

  • Are pregnant or may be pregnant.
  • Have an abnormally shaped uterus due to any cause, including uterine fibroids.
  • Have pelvic inflammatory disease.
  • Have ever had pelvic inflammatory disease, unless you have had a normal pregnancy since having PID.
  • Have had an infection of the uterine lining after childbirth (postpartum endometriosis) or after an abortion or miscarriage within the past three months.
  • Have or may have uterine or cervical cancer (cancers of the uterus or cervix).
  • Have an abnormal Pap smear that has not been evaluated.
  • Have or have had breast cancer or other progestin-sensitive cancers.
  • Have unexplained uterine bleeding.
  • Have an untreated vaginal or cervical infection.
  • Have liver disease or liver tumors.
  • Have a condition that increases your risk for pelvic infections, such as leukemia, AIDS, or IV drug abuse.
  • Have an IUD currently in place.
  • Are allergic to levonorgestrel, Mirena, Skyla, or any of the inactive components used to make the contraceptive. Your healthcare provider or pharmacist has a list of the inactive ingredients.

Final Thoughts

There are a number of situations in which levonorgestrel-releasing intrauterine system should not be used, as well as several warnings and precautions people should be aware of before using this form of birth control. However, it is possible that not all of these issues were discussed in this article. Therefore, talk with your healthcare provider about the specific safety concerns that may apply to you.

More Headlines in Precautions and Warnings With Levonorgestrel-Releasing Intrauterine System

↶ What Should I Tell My Healthcare Provider?
↶ Specific Levonorgestrel-Releasing Intrauterine System Precautions and Warnings
Last reviewed by: Kristi Monson, PharmD
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