Levothroid and Insomnia

A number of side effects have been reported with Levothroid, and insomnia appears to be one of them. Because insomnia is a common symptom of hyperthyroidism, it is possible that your Levothroid dosage may be too high if you experience insomnia while taking the drug. However, your insomnia symptoms may be completely unrelated to the medication.

Does Levothroid Cause Insomnia?

Levothroid® (levothyroxine sodium) is known to cause insomnia. However, the exact percentage of people who develop this side effect while taking the drug has not been reported (which is common with older medications, like Levothroid). Because insomnia may be a sign that your Levothroid dosage is too high, you should let your healthcare provider know if you develop any symptoms of insomnia while taking Levothroid.

What Exactly Is Insomnia?

Insomnia is a sleep disorder that often causes the following symptoms:
  • Having trouble falling asleep (often lying awake in bed for hours)
  • Waking up often during the night and having trouble going back to sleep
  • Waking up too early in the morning
  • Getting non-refreshing sleep.
Some people experience just one insomnia symptom, while others have all of them.

Is Insomnia With Levothroid a Bad Sign?

Insomnia is a common symptom of hyperthyroidism, which can occur if your Levothroid dosage is too high. However, it is also possible that your insomnia could be completely unrelated to Levothroid. The best way to find out if you are taking too much Levothroid is through a simple blood test. Also, you should be aware of other symptoms of hyperthyroidism, which may also signal that your dose is too high. Some of these symptoms include:
  • Feeling hot all the time and increased sweating
  • Heart palpitations
  • High blood pressure (hypertension)
  • Rapid heart rate (tachycardia)
  • Shakiness (tremors) or muscle weakness
  • An increased appetite, along with weight loss
  • Fever
  • Emotional changes
  • Chest pain
  • Difficult or painful breathing
  • Diarrhea, vomiting, or abdominal cramps (stomach cramps)
  • Hair loss (see Levothroid and Hair Loss)
  • Flushing
  • Menstrual problems
  • Infertility.

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Last reviewed by: Kristi Monson, PharmD
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