Advertisement

Levothroid Drug Interactions

Diabetes Drugs
When you first start Levothroid (or increase your dose), your healthcare provider may need to increase the dose of your diabetes medications. If you are taking diabetes medications, check with your healthcare provider before taking Levothroid.
Digoxin
Levothroid can make digoxin less effective, which can be dangerous. Check with your healthcare provider, as your digoxin dose may need to be increased.
Estrogens
Estrogens can lower the level of Levothroid in your blood, perhaps making it less effective. Your healthcare provider may need to adjust your Levothroid dose if you start or stop taking an estrogen medication.
Iron
Iron can bind to Levothroid in the digestive tract, decreasing the absorption of Levothroid into the body. Make sure to separate Levothroid and iron supplements by at least four hours.
Orlistat
Orlistat may decrease the absorption of Levothroid into the body. Your healthcare provider should check your thyroid function if you start (or stop) taking orlistat. Your Levothroid dosage may need to be adjusted.
Raloxifene
There have been reports that raloxifene may decrease the absorption of Levothroid into the body, although it is not clear if this is a significant drug interaction.
Rifampin
Taking Levothroid with rifampin may change the amount of Levothroid your body needs. As a result, your healthcare provider may need to adjust your Levothroid dosage.
Sucralfate
Sucralfate can bind to Levothroid in the digestive tract, decreasing the absorption of Levothroid into the body. Make sure to separate Levothroid and sucralfate by at least four hours.
Last reviewed by: Kristi Monson, PharmD
Advertisement
The Zen of Cancer Caregiving - Recharge Your Batteries!