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Liothyronine Dosage

For most mild cases of hypothyroidism, the usual starting liothyronine dosage is 25 mcg once daily. People with myxedema (a certain type of hypothyroidism) usually start with a dose of 5 mcg daily. The recommended starting dose of liothyronine for treating a goiter is also 5 mcg daily. For all of these conditions, your healthcare provider will generally increase your dose gradually as needed.

An Introduction to Liothyronine Dosages

The dose of liothyronine sodium (Cytomel®) your healthcare provider recommends will vary, depending on a number of factors, including:
  • The medical condition being treated
  • Other medications you may be taking
  • How you respond to liothyronine
  • Other medical conditions you may have.
As is always the case, do not adjust your dose unless your healthcare provider specifically instructs you to do so.

Dose of Liothyronine for a Low Thyroid

For most cases of mild underactive thyroid (hypothyroidism), the recommended starting dose is liothyronine 25 mcg once daily. Your healthcare provider may increase your dose by up to 25 mcg every one to two weeks. Most people end up taking 25 to 75 mcg of liothyronine a day.
For treating myxedema (a certain type of hypothyroidism), the recommended starting dose of liothyronine is 5 mcg once daily. Your healthcare provider may increase your dose by 5 or 10 mcg every one to two weeks as necessary until a dose of 25 mcg is reached. After that, your healthcare provider may increase your dose by 5 to 25 mcg every one or two weeks. Most people with myxedema end up taking a liothyronine dosage of 50 to 100 mcg a day. For myxedema coma (a more serious form of the disease), an injectable form of liothyronine (Triostat®) is usually preferred.
For infants with congenital hypothyroidism, the recommended starting liothyronine dose is 5 mcg once daily. Your child's healthcare provider may increase the dose by 5 mcg every three or four days as necessary. The dose will need to be increased as your child grows; most children age three and older need a typical adult dosage.
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Liothyronine Sodium Information

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