Lo Loestrin Fe Side Effects

Headaches, nausea, and breast tenderness are some of the most commonly reported side effects of Lo Loestrin Fe. Reactions to this contraceptive can also be potentially serious, so contact your healthcare provider if you experience problems such as chest pain, difficulty breathing, or speech changes. In most cases, however, side effects of this pill are mild and easy to treat.

An Introduction to Lo Loestrin Fe Side Effects

Just like any medicine, Lo Loestrin™ Fe (norethindrone/ethinyl estradiol) can cause side effects. However, not everyone who takes this contraceptive will have problems. In fact, most women tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with Lo Loestrin Fe. Your healthcare provider can discuss a more complete list with you.)

Common Side Effects of Lo Loestrin Fe

Lo Loestrin Fe has been studied extensively in clinical trials. In most clinical studies of medications, the side effects that occur in a group of people taking the drug are documented and then compared to those that occur in another group of people not taking the medicine (they usually take a placebo that does not contain any active ingredients).
As a result, it is possible to see what side effects occur, how often they appear, and how they compare to the group not taking the medicine. However, it is not possible to use a placebo in clinical trials for contraceptives, as this would lead to many unintentional pregnancies.
Based on the results of clinical studies, some of the most commonly reported side effects of Lo Loestrin Fe (occurring in more than 1 percent of women) included but were not limited to:
  • Nausea or vomiting -- in up to 7 percent of women
  • Headaches -- up to 7 percent
  • Breakthrough bleeding or spotting (bleeding between periods) or other menstrual irregularities -- up to 5 percent
  • Painful menstrual periods -- up to 4 percent
  • Weight "fluctuations" -- up to 4 percent
  • Breast tenderness -- up to 4 percent
  • Acne -- up to 3 percent
  • Abdominal pain (stomach pain) -- up to 3 percent
  • Anxiety -- up to 2 percent
  • Depression -- up to 2 percent.

More Headlines in Lo Loestrin Fe Side Effects

‣ Side Effects to Report
‣ Final Thoughts
Last reviewed by: Kristi Monson, PharmD
Pregnancy and Pain