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Lo Loestrin Fe Uses

How Does Lo Loestrin Fe Work?

Lo Loestrin Fe primarily prevents pregnancy by stopping ovulation (the maturation and release of eggs from the ovaries). However, it also prevents pregnancy in two other, minor ways. Lo Loestrin Fe alters the cervical mucus (the fluid of the cervix, which is the lower, narrow part of the uterus that is connected to the vagina), making it more difficult for sperm to enter the uterus. It also alters the lining of the uterus (called endometrium), making it less receptive to an embryo.
The first 24 tablets in each pack of Lo Loestrin Fe contain both of the active hormones. The next two tablets contain only the ethinyl estradiol (estrogen) hormone. The last two tablets do not contain any active hormones, but they do contain iron. The iron might possibly help prevent anemia that could occur due to blood loss during a woman's period, although it is questionable if taking iron two days a month really makes any difference.

Lo Loestrin Fe Uses in Children and Teens

Lo Loestrin Fe is approved for use in women of reproductive age. This means that it is not approved for use in girls who have not yet had their first menstrual periods.

Is It Used for Off-Label Reasons?

On occasion, your healthcare provider may recommend Lo Loestrin Fe for something other than the conditions discussed in this article. This is called an "off-label" use. At this time, off-label Lo Loestrin Fe uses include treatment of the following conditions:
  • Acne
  • Premenstrual dysphoric disorder (PMDD)
  • Heavy menstrual bleeding
  • Painful menstrual periods
  • Irregular menstrual periods.
Last reviewed by: Kristi Monson, PharmD
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