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Loestrin 24 Fe Drug Interactions

Loestrin 24 Fe Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Loestrin 24 Fe is combined with any of the drugs listed above.
Aminoglutethimide (Cytadren)
Combining Loestrin 24 Fe with aminoglutethimide may increase your risk of pregnancy. Talk with your healthcare provider before using these medications together. You may need to use a backup method of contraception (such as condoms).
Antibiotics
There have been many reports of accidental pregnancy occurring in women taking birth control pills and certain antibiotics. It is still uncertain how significant these interactions may be. Some antibiotics may be more likely to cause problems than others. Ask your healthcare provider if you need a backup method of contraception any time you take an antibiotic.
Aprepitant (Emend)
Aprepitant may make Loestrin 24 Fe less effective, perhaps increasing your chance of pregnancy. Talk with your healthcare provider before using these medications together. You may need to use a backup method of contraception.
Barbiturates
Barbiturates may cause your body to metabolize the hormones in Loestrin 24 Fe too quickly, increasing your risk of pregnancy. Ask your healthcare provider if you should use a different method of contraception while taking a barbiturate.
Cyclosporine (Gengraf, Neoral, Sandimmune)
Loestrin 24 Fe may increase the level of cyclosporine in your blood, increasing the chance of side effects of cyclosporine. Talk with your healthcare provider before taking these medications together. Your cyclosporine dose may need to be reduced, or you may need to switch to a different method of contraception.
Last reviewed by: Kristi Monson, PharmD
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