Clinical Effects of Lorcaserin

Lorcaserin has been studied in clinical trials that included people who were overweight or obese. Some people were given lorcaserin, while others were given a placebo (a similar product that does not contain any active ingredients). In these studies, everyone in the study also consumed a low-calorie diet and exercised. In one study, 47.1 percent of people who took lorcaserin for up to a year lost at least 5 percent of their body weight, compared to 22.6 percent of people who took the placebo.

When and How to Take This Medicine

Some general considerations to keep in mind during treatment with lorcaserin include the following:
  • This medication comes as a tablet. It is usually taken by mouth twice a day.
  • You can take lorcaserin with or without food. Try taking it with food if it seems to bother your stomach.
  • If you have not lost at least 5 percent of your weight within 12 weeks of treatment, your healthcare provider may recommend you stop using it. It is unlikely that lorcaserin will work for you.
  • This medicine is just one part of a complete weight-loss treatment plan that should also include diet and exercise.
  • Try to take this medication at the same times each day to keep an even level of the drug in your bloodstream.
  • For the medication to work properly, it must be taken as prescribed. This medicine will not work better if you take more than prescribed; however, taking more will increase your risk for side effects.

Dosing Information for Lorcaserin

There is only one standard recommended dose of lorcaserin. As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.
(Click Lorcaserin Dosage for more information.)
Last reviewed by: Kristi Monson, PharmD
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