LoSeasonique Warnings and Precautions

Specific Precautions and Warnings With LoSeasonique

Some warnings and precautions to be aware of prior to using LoSeasonique include the following:
  • Even though you will have fewer scheduled periods while taking LoSeasonique (only four periods per year), many women have breakthrough bleeding between periods. This bleeding may be inconvenient and unpredictable. Keep taking LoSeasonique as usual, but make sure to contact you healthcare provider if the bleeding is heavy.
  • Combined oral contraceptives increase the risk of blood clots, strokes, and heart attacks. These risks are quite small for healthy, young nonsmokers. Make sure to tell your healthcare provider if you have ever had a blood clot, stroke, heart attack, or chest pain.
  • LoSeasonique does not protect against HIV, AIDS, or other sexually transmitted diseases (STDs). In many cases, it is advisable to use condoms in addition to LoSeasonique.
  • Smoking cigarettes greatly increases the risk of serious LoSeasonique side effects (such as heart attacks, strokes, and blood clots). This risk is particularly high for smokers over the age of 35.
  • Early studies have suggested that combined oral contraceptives may slightly increase the risk of breast cancer or cervical cancer, although this is an unresolved and controversial issue (with more recent studies indicating that this may not really be a problem). Interestingly, combined oral contraceptives seem to help protect women against ovarian and uterine cancer.
  • Birth control pills are sometimes not the best contraceptive choice for obese women. They may be less effective in these women, and obese women may be at a higher risk for some of the serious LoSeasonique side effects.
  • Oral contraceptives increase the risk of benign (noncancerous) liver tumors. In rare cases, these tumors can rupture and cause serious problems.
  • Hormonal contraceptives (such as LoSeasonique) can make gallbladder disease worse. If you have had a problem with your gallbladder, this medication may not be the best contraceptive method for you.
  • LoSeasonique may increase blood sugar levels, particularly in women with diabetes. As a result, your healthcare provider may need to monitor you more closely. Let your healthcare provider know if you have any sudden vision changes, as this may be a sign of a blood clot in the eyes (a possible side effect of LoSeasonique and other hormonal contraceptives).
  • Hormonal contraceptives can increase your blood pressure. This can be a problem if you already have high blood pressure.
  • If you experience a migraine for the first time (or a change in your migraines if you have had them before) while taking LoSeasonique, contact your healthcare provider.
  • LoSeasonique can change your menstrual bleeding patterns. Some women have breakthrough bleeding (bleeding between periods), while others may not have a period at all. It is normal to have shorter and lighter periods while using LoSeasonique. However, if you notice any unusual changes in your bleeding patterns, let your healthcare provider know. If you miss a period, you should make sure you are not pregnant.
  • LoSeasonique can affect your cholesterol. Your healthcare provider may need to check your cholesterol levels after you start this medication, especially if you already have high cholesterol.
  • Sometimes, hormonal contraceptives can make depression worse. Let your healthcare provider know if you develop new or worsening depression symptoms while taking LoSeasonique.
  • Occasionally, LoSeasonique (as well as any other hormonal contraceptive) can cause eye changes that make it more difficult to wear contact lenses.
  • LoSeasonique can interact with a number of different medications (see LoSeasonique Drug Interactions for more information).
  • LoSeasonique is considered a pregnancy Category X medication. This means that it should not be used during pregnancy (see LoSeasonique and Pregnancy).
  • Contraceptive hormones (such as the ones in LoSeasonique) pass through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to taking the drug (see LoSeasonique and Breastfeeding). Combined hormonal contraceptives are generally not recommended for women who are breastfeeding.
Last reviewed by: Kristi Monson, PharmD
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