Effects of Lybrel

Lybrel was shown to be an effective birth control method in a large clinical trial. In this study, between one and three out of every 100 women who used it for a year became pregnant. This is very effective, compared to many other methods of contraception. For instance, up to 14 percent of women using condoms for a year will become pregnant.
Studies have also shown that more than half of women taking Lybrel for one year will not have any bleeding or spotting, but it often takes several months for this to occur. Some women will continue to have bleeding and spotting.

When and How to Use Lybrel

Some general considerations for when and how to use the medication include the following:
  • Lybrel comes in the form of a tablet that is taken by mouth once a day.
  • You can take it with food or on an empty stomach. If it bothers your stomach, try taking it with food.
  • Each pack of Lybrel contains 28 pills. Be sure to take them in order. Once you finish a pack, start a new pack right away.
  • It is normal to experience breakthrough bleeding or spotting while taking Lybrel. Keep taking it as normal.
  • It is very important to take Lybrel every day, at the same time each day. Try to pick a time that is easy to remember (such as at bedtime or breakfast). If you have trouble remembering, please talk with your healthcare provider, as missing pills increases your risk of pregnancy.
  • Make sure you know exactly what to do if you miss any pills. In some circumstances, you may need to use a backup method of contraception (such as condoms) for seven days.
  • For the medication to work properly, it must be taken as prescribed.

Dosing Information

There is only one standard dose of Lybrel, regardless of age, weight, or medical conditions. As always, do not adjust your dose unless your healthcare provider specifically instructs you to do so.
(Click Lybrel Dosage for more information.)
Last reviewed by: Kristi Monson, PharmD
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