Women Home > Precautions and Warnings With Medroxyprogesterone Intramuscular Injection
You may not be able to use medroxyprogesterone intramuscular injection if you have breast cancer, liver problems, or if you are pregnant. Other precautions for medroxyprogesterone intramuscular injection include warnings of potential problems this drug may cause, such as bone loss, liver problems, and fluid retention. It is also important for your healthcare provider to know about any other medications you are taking.
What Should I Tell My Healthcare Provider Before Using Medroxyprogesterone Intramuscular Injection?Talk with your healthcare provider prior to receiving medroxyprogesterone intramuscular injection (Depo-Provera®) if you have:
- Unexplained vaginal bleeding
- Breast cancer, a family history of breast cancer, or a personal history of breast cancer
- An abnormal mammogram or breast problems, such as breast lumps or bleeding from your nipples
- Irregular menstrual periods
- Heart disease
- A history of a heart attack, stroke, or blood clots
- High blood pressure (hypertension)
- Liver disease, such as hepatitis, cirrhosis, or liver failure
- Kidney disease, such as kidney failure (renal failure)
- Osteoporosis or a history of fracturing a bone, or have a family history of osteoporosis
- Migraine headaches
- Seizure disorder (epilepsy)
- An alcohol problem or drink large quantities of alcohol
- Anorexia nervosa (an eating disorder)
- Any allergies, including to foods, dyes, or preservatives.
- Smoke cigarettes
- Are pregnant or thinking of becoming pregnant (see Depo-Provera and Pregnancy)
- Are breastfeeding (see Depo-Provera and Breastfeeding).