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When certain medications are combined with Mircette, drug interactions could occur. Some of these interactions can decrease the effectiveness of Mircette, increasing your risk of pregnancy. Among the medications that can negatively interact with Mircette are antibiotics, barbiturates, and some seizure medications. To avoid any complications, make sure to talk to your healthcare provider about possible interactions with Mircette that may apply to you.

An Introduction to Mircette Drug Interactions

Mircette® (desogestrel/ethinyl estradiol) can potentially interact with numerous other medicines. Many of these interactions can be severe enough to cause accidental pregnancy. Some of the medicines that may lead to Mircette interactions include:
  • Aminoglutethimide (Cytadren®)
  • Antibiotics
  • Aprepitant (Emend®)
  • Atorvastatin (Lipitor®) or combination medications that contain atorvastatin (Caduet®, Liptruzet™)
  • Barbiturate medications, including (but not limited to):
    • Amobarbital (Amytal®)
    • Butalbital (Fioricet®, Fiorinal®)
    • Pentobarbital (Nembutal®)
    • Phenobarbital (Luminal®)
    • Secobarbital (Seconal®)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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