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You may have an increased risk for side effects or other potentially serious problems if you combine certain products with Vandazole. Interactions may occur if this vaginal gel is combined with products like alcohol, lithium, and warfarin. To help avoid these adverse reactions, make sure your healthcare provider has up-to-date information on all medications, vitamins, and supplements you are taking.
An Overview of Interactions With VandazoleVandazole® (metronidazole vaginal gel) may interact with a few other medications. Some of the drugs that may react with Vandazole include but are not limited to:
- Amprenavir oral solution (Agenerase®)
- Disulfiram (Antabuse®)
- Eplerenone (Inspra™)
- Lithium (Eskalith®, Lithobid®)
- Maraviroc (Selzentry™)
- Ranolazine (Ranexa®)
- Warfarin (Coumadin®, Jantoven®).
Vandazole Drug Interactions ExplainedThe following sections explain in detail the potentially negative reactions that can occur when Vandazole is combined with any of the drugs listed above.
The standard advice is that people taking metronidazole products should not drink alcohol. However, this interaction is probably less likely to occur when metronidazole is applied vaginally, as it is with Vandazole. However, there is some uncertainty about the validity of this interaction (see Metronidazole and Alcohol).
Officially, the prescribing information for Vandazole states that women should stop consuming alcohol during treatment with this product and for at least three days after the last dose.