Women Home > Vandazole Side Effects

In most cases, reactions to Vandazole tend to be minor and treated easily. Some of the most commonly reported side effects of Vandazole include vaginal yeast infections, itching, and painful menstrual cramping. Notify your healthcare provider immediately if you are using Vandazole and you experience numbness in your hands or feet, seizures, or severe skin reactions.

An Introduction to Vandazole Side Effects

Just like any medicine, Vandazole® (metronidazole vaginal gel) can cause side effects. However, not everyone who uses the medication will have problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with Vandazole. Your healthcare provider can discuss a more complete list with you.)

Common Side Effects of Vandazole

Vandazole has been studied extensively in clinical trials. In these studies, the side effects that occurred in a group of people using the drug were carefully documented. In these studies, the most common reactions included:
  • Vaginal yeast infection -- in up to 12 percent of women
  • Headache -- up to 7 percent
  • Itching -- up to 6 percent
  • Abdominal (stomach) pain -- up to 5 percent
  • Nausea -- up to 3 percent
  • Painful menstrual cramping -- up to 3 percent.
Other common side effects, occurring in 1 percent to 3 percent of people, included:
  • Painful menstrual cramping
  • Sore throat
  • Rash
  • Infection
  • Diarrhea
  • Breast pain
  • Breakthrough bleeding or spotting (between periods).
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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