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Women who have bacterial vaginosis (BV) and are not pregnant may receive Vandazole. This prescription drug comes in the form of a vaginal gel that is inserted once a day for five days. It is an antibiotic that kills certain types of vaginal bacteria. Most women tolerate this medicine well; however, side effects are possible and may include itching, headaches, and vaginal yeast infections.

What Is Vandazole?

Vandazole® (metronidazole vaginal gel) is a prescription medication approved for the treatment of bacterial vaginosis (BV) in women who are not pregnant. Bacterial vaginosis is a condition involving an overgrowth of certain types of vaginal bacteria. Vandazole comes as a gel that is used once a day for five days.

Who Makes This Medication?

This medication is made by Upsher-Smith Laboratories, Inc.

How Does Vandazole Work?

This medication contains metronidazole, an antibiotic that kills certain types of bacteria. This allows the normal vaginal "flora" (the bacteria that reside in the vagina) to return to a more normal and healthy balance.

When and How to Use It

Some general considerations to keep in mind during treatment with Vandazole include the following:
  • Using the applicator that comes with Vandazole, insert the gel once a day for five days. The box should come with five applicators and instructions for use.
  • Using this medication at bedtime is usually more convenient, as laying down helps decrease the bothersome "leakage" of the product that often occurs.
  • You should not have sex while using this medication. Do not use tampons, douches, or other vaginal products during Vandazole treatment.
  • For the medication to work properly, it must be used as prescribed. Do not stop using it too soon, even if you are feeling better.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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