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Xeomin is a product prescribed for several uses, such as to treat eyelid twitching, relieve neck pain, and improve the appearance of wrinkles between the eyebrows. It is given as an injection and works to relax muscles by affecting nerve signals. The effects are not permanent. Side effects may include dry eyes, droopy eyelids, and difficulty swallowing.

What Is Xeomin?

Xeomin® (incobotulinumtoxinA) is a prescription injection that is approved to:
  • Temporarily improve the appearance of wrinkles between the eyebrows (frown lines)
  • Relieve neck pain and abnormal head position associated with cervical dystonia (a certain kind of muscle spasm of the head and neck)
  • Treat eyelid twitching or spasms (known medically as blepharospasm) in people previously treated with Botox®.
(Click Xeomin Uses for more information on this topic, including possible off-label uses.)

Who Makes This Medication?

Xeomin is made by Merz Pharmaceuticals, LLC.

How Does Xeomin Work?

Xeomin is a toxin produced by Clostridium botulinum bacteria. The drug works by decreasing nerve signals to muscles, which helps them to relax. It enters nerve cells and inhibits the release of acetylcholine, a chemical that transmits signals from nerve to nerve. The actions of the medication are not permanent, and the muscle will eventually recover and return to its previous state.

When and How to Receive It

Some general considerations to keep in mind during treatment with Xeomin include the following:
  • The drug comes in injectable form. It is injected directly into the muscles that are causing the problems.
  • Your healthcare provider may choose to use an anesthetic cream to numb your skin before the injection, but this is not always necessary. If you are worried about pain, ask your healthcare provider about using an anesthetic cream.
  • The effects of this drug are not permanent. You will need to receive injections periodically to maintain the effects.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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