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Metronidazole Vaginal Application

If you have bacterial vaginosis, your healthcare provider may recommend treatment with metronidazole vaginal gel (MetroGel-Vaginal®). This prescription medication comes in the form of a gel that is inserted vaginally either once or twice daily for five days.
Application of metronidazole vaginal gel consists of using a full applicator (approximately 5 grams) of gel inserted vaginally. Although once-daily dosing is more convenient, some healthcare providers prefer twice-a-day dosing, which may be more effective. If you are using this medication just once a day, it may be more convenient to use it at bedtime, as lying down helps decrease the bothersome "leakage" of the product that often occurs.
(For more information, click Metronidazole Vaginal Gel Dosage. This full-length article focuses on more application techniques and dosing guidelines for this medication.)
Last reviewed by: Kristi Monson, PharmD
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