Metronidazole Vaginal Gel Dosage

When prescribing metronidazole vaginal gel, a healthcare provider will determine whether you should use this medicine once or twice a day. There is only one strength of metronidazole vaginal gel, and the dosing instructions call for one applicator full of the gel to be inserted into the vagina for five days. Some healthcare providers consider twice-daily dosing more effective.

An Introduction to Your Metronidazole Vaginal Gel Dosage

The dose of metronidazole vaginal gel (MetroGel-Vaginal®) your healthcare provider recommends will vary, largely depending on whether once-a-day or twice-a-day dosing is preferred.

Dosing Guidelines for Metronidazole Vaginal Gel

The standard instructions for metronidazole 0.75% vaginal gel are to insert one full applicator (approximately 5 grams of the gel) once or twice a day for five days. Once-daily dosing is obviously more convenient, but some healthcare providers prefer twice-a-day dosing, with the thought that perhaps twice-daily dosing is more effective.

General Information on Using Metronidazole Vaginal Gel

Some considerations to keep in mind during treatment with metronidazole vaginal gel include the following:
  • Apply this medication using the enclosed applicator once or twice a day for five days. The box should come with five applicators and instructions for use.
  • If you are using it twice a day, you will need to reuse the applicators (wash them in warm soapy water between uses). If you are using metronidazole vaginal gel just once a day, you will have enough applicators and can simply throw them away after use.
  • If you are using this medication just once a day, using it at bedtime is usually more convenient, as lying down helps decrease the bothersome "leakage" of the product that often occurs.
  • You should not have sex while using metronidazole vaginal gel.
  • For the medication to work properly, it must be used as prescribed.
  • If you are unsure about anything related to your dosage or metronidazole vaginal gel dosing in general, please talk to your healthcare provider or pharmacist.
Last reviewed by: Kristi Monson, PharmD
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