Mifepristone After 7 Weeks

Mifepristone (Mifeprex®, Korlym™) is approved to cause an abortion in women who are 7 weeks pregnant or less. It is also approved for daily use to treat high blood sugar levels caused by high cortisol levels in people with Cushing's syndrome. However, this drug can also be used for "off-label," or unapproved, uses as well. For example, a healthcare provider may prescribe mifepristone off-label to cause an abortion after 7 weeks of pregnancy.
Mifepristone comes as tablets that are taken as a one-time dose in a healthcare setting, such as a healthcare provider's office or clinic, when used to end a pregnancy. It may be a good option for women who are trying to avoid a surgical abortion.
The medicine works by blocking the action of progesterone, a hormone necessary to maintain a pregnancy. By blocking progesterone, mifepristone causes the lining of the uterus to become soft and break down, ending the pregnancy.
(Click What Is Mifepristone Used For? for more details on this abortion pill. This Web resource contains more information on when and how it is taken, other off-label uses, and more.)
Last reviewed by: Kristi Monson, PharmD
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