Mifepristone Dosage

If you have decided to terminate a pregnancy and your healthcare provider prescribes mifepristone, your one-time dosage will consist of three tablets. This drug is given in a healthcare setting, such as a medical office or clinic. Two days later, you will need to see your healthcare provider again to determine if the pregnancy was terminated or if you need a different medication.

An Introduction to Your Dosage of Mifepristone

The dose of mifepristone (Mifeprex®, Korlym™) your healthcare provider recommends may vary, based on a number of factors, such as:
  • Why you are taking the medication
  • How you respond to it
  • Other medications you may be taking
  • Other medical conditions you may have.

As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.

Mifepristone Dosing to End a Pregnancy

The usual recommended regimen to end a pregnancy is a one-time dose of mifepristone 600 mg (three tablets). You will take your dose in a healthcare setting, such as your healthcare provider's office or a clinic, after receiving a physical exam.
Two days later, you will need to return to your healthcare provider's office. He or she will do a physical exam or give you an ultrasound to determine if you are still pregnant. If you are still pregnant, you will be given misoprostol (Cytotec®). The usual misoprostol dosage is 400 mcg (usually given as two 200-mcg tablets).
Approximately two weeks after taking mifepristone, you will return to your healthcare provider's office once again. Your healthcare provider will give you a physical exam or an ultrasound to make sure mifepristone successfully ended your pregnancy. If you are still pregnant, your healthcare provider will talk to you about other options for ending your pregnancy, including a surgical abortion.
Last reviewed by: Kristi Monson, PharmD
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