Mifepristone Effectiveness

If it has been 49 days or less since your last menstrual period and you have decided to terminate the pregnancy, a healthcare provider may recommend an abortion pill called mifepristone (Mifeprex®, Korlym™). This prescription medication comes as a tablet and works by causing the lining of the uterus to soften and break down.
When used as directed, mifepristone treatment usually ends a pregnancy. However, this abortion pill is not always successful. If this drug does not work, you may need to have a surgical procedure to end your pregnancy. In studies on the effectiveness of mifepristone, about 5 percent to 8 percent of women needed a surgical procedure to end their pregnancy or to stop excessive bleeding after taking mifepristone.
Mifepristone is also approved to treat high blood sugar levels (hyperglycemia) caused by high cortisol levels (hypercortisolism) in people with Cushing's syndrome. In clinical studies, mifepristone was shown to reduce blood sugar levels in people with endogenous Cushing's syndrome with diabetes and high cortisol levels. In this study, 60 percent of people given mifepristone had at least a 25 percent decrease in their blood sugar levels.
(Click What Is Mifepristone Used For? to learn more about the effectiveness of this drug. This article also takes a closer look at using this abortion pill in general, including what to expect during treatment, possible off-label uses, and more.)
Last reviewed by: Kristi Monson, PharmD
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