Side Effects of Mirena

Side effects are possible with Mirena. However, not every woman who uses the contraceptive will experience side effects. In fact, most women tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are easily treated by you or your healthcare provider. Serious side effects are less common.
Common side effects of Mirena include, but are not limited to:
(Click Mirena Side Effects to learn more, including potentially serious side effects that you should report immediately to your healthcare provider.)

Drug Interactions

It is not known if Mirena interacts with any other medications (see Mirena Drug Interactions).

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to using Mirena if you have:
  • A history of pelvic inflammatory disease (PID)
  • Had a serious pelvic infection
  • More than one current sexual partner (or if your partner has more than one sexual partner)
  • A weakened immune system due to HIV or AIDS, cancer, or IV drug abuse
  • Uterine cancer or cervical cancer
  • Unexplained vaginal bleeding
  • Liver disease, such as liver failure, cirrhosis, hepatitis, or liver tumors
  • Breast cancer (or a history of breast cancer)
  • Had an ectopic pregnancy (a "tubal" pregnancy) or are at high risk for an ectopic pregnancy
  • An intrauterine device (IUD) still in place
  • An abnormally shaped uterus or uterine fibroids
  • Diabetes
  • Had a blood clot or a clotting disorder
  • Heart disease or problems with your heart valves
  • Any allergies, including allergies to medications, foods, dyes, or preservatives.
Also, let your healthcare provider know if you:
Make sure to tell your healthcare provider about any other medications you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
(Click Mirena Warnings and Precautions to learn more, including information on who should not use Mirena.)
Last reviewed by: Kristi Monson, PharmD
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